Functional and Integrative Genomics

We provide advanced and personalised support and consulting in bioinformatics and biostatistics for the scientific community of EPFL as well as for other Institutes.
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PJ Fabre et al. Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development. 2018 #
A Kfoury et al. AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress. 2018 #
PJ Fabre et al. Large scale genomic reorganization of topological domains at the HoxD locus. 2017 #
C McDermott-Roe et al. Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function. 2017 #
MN Loviglio et al. Chromosomal contacts connect loci associated with autism, BMI and head circumference phenotypes. 2017 #
MN Loviglio et al. Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics. 2016 #
C Deluz et al. A role for mitotic bookmarking of SOX2 in pluripotency and differentiation. 2016 #
M Vieux-Rochas et al. Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain. 2015 #
D Noordermeer et al. Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci. 2014 #
HTSstation FP David et al. HTSstation: a web application and open-access libraries for high-throughput sequencing data analysis. 2014 #
A Cerase et al. Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy. 2014 #
JM Woltering et al. Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits. 2014 #
G Andrey et al. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. 2013 #
N Gheldof et al. Structural variation-associated expression changes are paralleled by chromatin architecture modifications. 2013 #
S Delpretti et al. Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding. 2013 #
G Andrey et al. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. 2013 #
N Gheldof et al. Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method. 2012 #
D Noordermeer et al. The dynamic architecture of Hox gene clusters. 2011 #
N Soshnikova et al. Functional analysis of CTCF during mammalian limb development. 2010 #
M Leleu et al. Processing and analyzing ChIP-seq data: from short reads to regulatory interactions. 2010 #
Marion LeleuBioinformatician AAB026 30944
Marion is a senior bioinformatician providing support and consulting in bioinformatics and biostatistics.
With a 10+ years experience in this field and an educational background in computer science and data mining (PhD), Marion will work in close collaboration with you to give you all the support you need.
Bastien MangeatHead of GECF SV1841 37113

On-demand Bioinformatics Tools

We propose on-demand data integration as well as conception and development of bioinformatics databases/applications. This service is open to SV laboratories and core facilities.
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Fabrice DavidBioinformatician AAB026 30903
Christian IseliCo-head of BICC AAB021 0