Services

Functional and Integrative Genomics

We provide advanced and personalised support and consulting in bioinformatics and biostatistics for the scientific community of EPFL as well as for other Institutes.
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Fabre PJ et al. Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development. 2018 BMC biology
Kfoury A et al. AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress. 2018 The EMBO journal
Fabre PJ et al. Large scale genomic reorganization of topological domains at the HoxD locus. 2017 Genome biology
McDermott-Roe C et al. Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function. 2017 PloS one
Loviglio MN et al. Chromosomal contacts connect loci associated with autism, BMI and head circumference phenotypes. 2017 Molecular psychiatry
Loviglio MN et al. Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics. 2016 Genome medicine
Deluz C et al. A role for mitotic bookmarking of SOX2 in pluripotency and differentiation. 2016 Genes & development
Vieux-Rochas M et al. Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain. 2015 Proceedings of the National Academy of Sciences of the United States of America
Noordermeer D et al. Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci. 2014 eLife
HTSstation David FP et al. HTSstation: a web application and open-access libraries for high-throughput sequencing data analysis. 2014 PloS one
Cerase A et al. Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy. 2014 Proceedings of the National Academy of Sciences of the United States of America
Woltering JM et al. Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits. 2014 PLoS biology
Andrey G et al. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. 2013 Science (New York, N.Y.)
Gheldof N et al. Structural variation-associated expression changes are paralleled by chromatin architecture modifications. 2013 PloS one
Delpretti S et al. Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding. 2013 Cell reports
Andrey G et al. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. 2013 Science (New York, N.Y.)
Gheldof N et al. Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method. 2012 Methods in molecular biology (Clifton, N.J.)
Noordermeer D et al. The dynamic architecture of Hox gene clusters. 2011 Science (New York, N.Y.)
Soshnikova N et al. Functional analysis of CTCF during mammalian limb development. 2010 Developmental cell
Leleu M et al. Processing and analyzing ChIP-seq data: from short reads to regulatory interactions. 2010 Briefings in functional genomics
Marion LeleuBioinformatician AAB026 30944
Marion is a senior bioinformatician providing support and consulting in bioinformatics and biostatistics.
With a 10+ years experience in this field and an educational background in computer science and data mining (PhD), Marion will work in close collaboration with you to give you all the support you need.
Bastien MangeatHead of GECF SV1841 37113

On-demand Bioinformatics Tools

We propose on-demand data integration as well as conception and development of bioinformatics databases/applications. This service is open to SV laboratories and core facilities.
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Fabrice DavidBioinformatician AAB026 30903
Bastien MangeatHead of GECF SV1841 37113
Gaƫl AnexHead of SV-IT AAB119 34934